About 4:40am Police were called to a residence in Mulga Street, Kununurra, in relation to an injured woman.
Police attended the scene and located the 25 year old woman, who had a serious leg injury consistent with a stab wound.
St John Ambulance attended the residence and the injured woman was taken to Kununurra Hospital with critical injuries. Tragically, the injured woman passed away later in the day.
Homicide Squad detectives and forensic specialists from Perth travelled to Kununurra yesterday afternoon.
A 30 year old man, who is known to the woman, is currently assisting with the investigation.
Anyone with information regarding this incident is asked to call Crime Stoppers on 1800 333 000 or report the information online at www.crimestopperswa.com.au